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Table 2 MR and water content data.

From: Magnetic resonance imaging indicators of blood-brain barrier and brain water changes in young rats with kaolin-induced hydrocephalus

 

Pre- injection

Control 1 week

Hydrocephalus 1 week post kaolin

Control 3 weeks

Hydrocephalus 3 weeks post kaolin

Ventricle/brain area ratio

0.001 ± .001

0.002 ± .002

0.063 ± .021 **

0.006 ± .004

0.256 ± .048 **

T1 dorsal cortex

1.83 ± .05

1.88 ± .02

2.07 ± .05 **

1.81 ± .01

2.05 ± .08 **

T1 lateral cortex

1.78 ± .04

1.81 ± .01

1.86 ± .02 *

1.77 ± .01

1.76 ± .03

T1 striatum

1.71 ± .05

1.77 ± .02

1.80 ± .02

1.75 ± .01

1.76 ± .02

T1 white matter

1.72 ± .08

1.75 ± .01

2.87 ± .21 **

1.64 ± .03

2.77 ± .24 **

T2 dorsal cortex

50.5 ± 0.8

49.0 ± 1.9

53.0 ± 2.2

50.5 ± 0.1

55.7 ± 4.4

T2 lateral cortex

48.4 ± 0.3

47.3 ± 2.1

50.3 ± 0.5

49.1 ± 0.3

48.4 ± 1.1

T2 striatum

50.0 ± 0.3

47.8 ± 1.8

50.0 ± 0.4

49.5 ± 0.2

54.8 ± 3.6

T2 white matter

49.2 ± 0.7

49.1 ± 3.5

106.2 ± 11.1 **

49.5 ± 0.6

110.5 ± 17.7 **

ADCx dorsal cortex

716 ± 37

1054 ± 137

1020 ± 152

906 ± 112

1155 ± 132

ADCy dorsal cortex

1238 ± 24

1527 ± 170

1673 ± 109

1704 ± 200

1531 ± 140

ADCx lateral cortex

929 ± 32

1221 ± 151

1450 ± 215

1090 ± 73

930 ± 97

ADCy lateral cortex

896 ± 25

1145 ± 105

1720 ± 207

1239 ± 148

1109 ± 135

ADCx striatum

705 ± 24

992 ± 135

968 ± 126

892 ± 63

706 ± 84

ADCy striatum

1003 ± 20

1297 ± 142

1380 ± 105

1433 ± 184

1233 ± 177

ADCx white matter

1260 ± 67

1578 ± 174

2359 ± 329 *

1436 ± 112

2061 ± 234 *

ADCy white matter

851 ± 27

1158 ± 129

1954 ± 182 **

1253 ± 180

1958 ± 141 **

Density - dorsal cortex

1.034 ± .001 **

1.037 ± .001

1.036 ± .001

1.038 ± .001

1.036 ± .001 **

Density - white matter

1.032 ± .001 *

1.035 ± .001

1.033 ± .001

1.036 ± .001

1.033 ± .001 **

Water content - dorsal parietal cerebrum

81.59 ± .14**

80.52 ± .13

82.36 ± .51**

79.20 ± .20

83.23 ± .49 **

Water content - basal cerebrum

81.16 ± .32 **

79.97 ± .13

80.76 ± .24 *

79.21 ± .21

79.93 ± .19 *

  1. T1 and T2 - longitudinal and transverse relaxation times (msec). ADC - apparent diffusion coefficients (μm2/sec). All values are mean ± standard error. Age groups were compared with ANOVA. Significant differences between the pre-injection group and the 3-week control group are shown in the pre-injection column. Control and hydrocephalus groups of same age were compared with Student's t test. Differences between them are shown in the hydrocephalus columns, * p < 0.05, ** p < 0.01.
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Fluids and Barriers of the CNS

ISSN: 2045-8118