Magnetic resonance imaging indicators of blood-brain barrier and brain water changes in young rats with kaolin-induced hydrocephalus

Table 1 Animal age, weight and sample size.

GROUP	Pre-injection	Control 1 week	Hydrocephalus 1 week post kaolin	Control 3 weeks	Hydrocephalus 3 weeks post kaolin
Body weight at time of cisterna magna injection (g)	-	84.3 ± 10.2	72.0 ± 7.4	86.0 ± 2.8	80.9 ± 1.6
Age at time of study (weeks)	3.5	5	5	7	7
Body weight at time of study (g)	79.2 ± 6.3 **	131.8 ± 10.5	97.2 ± 6.9 *	262.8 ± 10.6	185.0 ± 13.8 **
Magnetic resonance data: sample size	4	9	12	8	7
Water content/density: sample size	5	4	5	4	8

All values are mean ± standard error. Age groups were compared with ANOVA. Significant differences between the pre-injection group and the 3-week control group are shown in the pre-injection column. Control and hydrocephalus groups of same age were compared with Student's t test. Differences between them are shown in the hydrocephalus columns, * p < 0.05, ** p < 0.01.

ISSN: 2045-8118