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Figure 3 | Fluids and Barriers of the CNS

Figure 3

From: Vascular endothelial growth factor blockade alters magnetic resonance imaging biomarkers of vascular function and decreases barrier permeability in a rat model of lung cancer brain metastasis

Figure 3

Effect of bevacizumab on tumor blood volume. Steady-state ΔR2* maps of relative cerebral blood volume (SS-rCBV) were measured in intracerebral A549 human lung adenocarcinoma xenografts. A) SS-rCBV in representative animals comparing control left hemisphere and tumor (right hemisphere, arrows) before and after saline (SAL) or bevacizumab (BEV). High rCBV is seen as mottled hot spots of hyperintensity. B) Normalized SS-CBV in tumors in the saline and bevacizumab-treatment tumors (n = 8 per group). Data are shown as mean ± standard error of the mean change from baseline.

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Fluids and Barriers of the CNS

ISSN: 2045-8118