Skip to main content
Figure 1 | Fluids and Barriers of the CNS

Figure 1

From: Vascular endothelial growth factor blockade alters magnetic resonance imaging biomarkers of vascular function and decreases barrier permeability in a rat model of lung cancer brain metastasis

Figure 1

Bevacizumab slows the growth of brain metastases. The volume of intracerebral A549 human lung adenocarcinoma tumor was determined using T2-weighted MRI. A) Representative tumors are shown for pretreatment (yellow) and post-treatment (red) in the saline control (SAL) and bevacizumab-treated (BEV) animals. A 3-dimensional representation is shown for each tumor. The axis labels are A, anterior, L, left, and S, superior. B) Normalized tumor growth in saline control and bevacizumab treated animals (n = 8 per group). Data are shown as mean ± standard error of the mean change from baseline. * P = 0.003 versus the saline control group.

Back to article page

Fluids and Barriers of the CNS

ISSN: 2045-8118