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Figure 5 | Fluids and Barriers of the CNS

Figure 5

From: Potential for intranasal drug delivery to alter cerebrospinal fluid outflow via the nasal turbinate lymphatics

Figure 5

Delivery of pharmacological agents alters CSF outflow resistance. To address whether a correlation existed between an overall drug effect and resistance, data points from all agents under no drug treatment (NT), the delivery of the first set of agents (drug conc.#1; 50 μM NA, 10 μM L-NMMA, 0.1 μM U46619) and the delivery of the second set of agents (drug conc.#2; 500 μM NA, 100 μM L-NMMA, 1 μM U46619) were plotted against resistance to outflow, which was derived from the linear regression analysis of the raw data. The straight line linking the averages within each treatment group was calculated with the Pearson correlation test.

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Fluids and Barriers of the CNS

ISSN: 2045-8118