Figure 5From: Leukocyte infiltration across the blood-spinal cord barrier is modulated by sleep fragmentation in mice with experimental autoimmune encephalomyelitisEffects of EAE on the spleen in mice at day 16 after induction: SF had no additional effect besides that of EAE to modulate peripheral immune cell proliferation (n = 8 /group). (A) EAE induced significant splenomegaly. (B) Gating of Gr1 and CD11b (+) populations with double labeling. (C) The total number of Gr1+CD11b+ cells was increased by EAE but SF had no additional effect. *: p < 0.05; **: p < 0.01.Back to article page