Table 3 Uptake of bacterial melanin by CNS and CNS regions after intravenous bolus injection
From: Bacterial melanin crosses the blood–brain barrier in rat experimental model
CNS region | Tissue/serum ratio (μl/g) |
|---|---|
Frontal cortex | 29.5 ± 1.9 |
Parietal cortex | 22.2 ± 2.7 |
Occipital cortex | 21.8 ± 1.8 |
Hypothalamus | 36.6 ± 6.3 |
Thalamus | 44.8 ± 8.4 |
Substantia nigra | 60.7 ± 10.2 |
Hippocampus | 28.2 ± 3.1 |
Cerebellum | 32.1 ± 3.2 |
Midbrain | 29.4 ± 2.8 |
Pons medulla | 26.5 ± 1.8 |
Cervical spinal cord | 33.3 ± 2.9 |
Thoracic spinal cord | 28.2 ± 2.8 |
Lumbar spinal cord | 58.2 ± 7.3 |
Whole CNS | 26,7 ± 2.8 |