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Figure 2 | Fluids and Barriers of the CNS

Figure 2

From: Th1 and Th17 but no Th2-related cytokine spectrum in the cerebrospinal fluid of children with Borrelia-related facial nerve palsy

Figure 2

Concentrations of cytokines related to the adaptive immunity in cerebrospinal fluid (CSF) and serum: a-b) IL-4 and IL-13 /Th2 related cytokines – only IL-4 was increased in CSF of controls in comparison to serum, c-f) IFN-γ and TNF-α /Th1 related cytokines and IL-17/ Th17 related cytokine were strikingly increased in CSF of BPFNP, f) IL-10 regulatory cytokine was strikingly increased in CSF and serum of BPFNP; BPFNP (n = 20) children with Borrelia-related facial palsy; NIPFNP (n = 14) children with non-inflammatory “idiopathic” facial palsy “; Controls (n = 23); P-values are indicated: * p < 0,05; ** p < 0,005; *** p < 0,0005; **** p < 0,0001.

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