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Table 2 The CSFP pulse during lumbar puncture versus ICP pulse during over-night ICP monitoring

From: Cerebrospinal fluid pulse pressure amplitude during lumbar infusion in idiopathic normal pressure hydrocephalus can predict response to shunting

Over-night ICP monitoring*

Lumbar puncture

ICP wave amplitude

CSFP wave amplitude during opening phase

CSF wave amplitude during lumbar infusion

 

< 2 mmHg

≥ 2 mmHg

< 4 mmHg

≥ 4 mmHg

< 4 mmHg (n = 20)

17

3

12

8

≥ 4 mmHg (n = 42)

17

25

5

37

Statistics

Sensitivity = 60; Specificity = 85

PPV = 89; NPV = 50

Sensitivity = 88; Specificity = 60

PPV = 82; NPV = 71

  1. *Mean ICP wave amplitude from the period 11 p.m. to 7 a.m.