Figure 9
From: Hydrocephalus induces dynamic spatiotemporal regulation of aquaporin-4 expression in the rat brain
Correlation between quantitative MRI and relative AQP4 expression. Plots of lateral ventricular volume vs. relative aquaporin-4 expression (A) and periventricular apparent diffusion coefficient value vs. relative aquaporin-4 expression (B) in both controls, hydrocephalic (two days, 2 D, one week,1W and two weeks, 2W) and non-hydrocephalic kaolin-injected animals. In hydrocephalic animals we found a significant linear positive correlation between lateral ventricular volume and periventricular aquaporin-4 expression (r2 = 0.33, p = 0.002). No correlation between periventricular apparent diffusion coefficient value and relative aquaporin-4 expression was found.