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Figure 3 | Cerebrospinal Fluid Research

Figure 3

From: Co-localization and regulation of basic fibroblast growth factor and arginine vasopressin in neuroendocrine cells of the rat and human brain

Figure 3

Co-localization of FGF2 and AVP in human magnocellular neurons: (A) Single labeled LRSC-stained anti-FGF2 and (B) FITC-stained anti-AVP images generated from 25 and 26 sequential 0.1 μm slices at 1000X magnification, respectively. Note differences in the relative distribution of reaction product within this neuron of the human SON. FGF2 is concentrated in small granular structures in the apical portion of the neuronal perikaryon (A). AVP, in contrast, is more homogeneously distributed in neuronal cytoplasm. (C) Composite-merged view of LRSC-labeled anti-FGF2 and FITC-labeled anti-AVP immunoreactivities generated from 51 sequential 0.1 μm slices at 1000X. Note the tendency for co-localized yellow reaction products to be concentrated in the apical portion of this neuronal cell body.

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