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Figure 4 | Cerebrospinal Fluid Research

Figure 4

From: Cerebrospinal fluid may mediate CNS ischemic injury

Figure 4

Overview of mechanisms underlying the CNS vulnerability to ischemia. Blood brain barrier and Blood-CSF barrier determine the low protein concentration in the cerebrospinal fluid and the interstitial fluid. A large amount of free fluid causes the CNS cells to consume more energy to maintain normal intracellular environment. The positive intracranial pressure facilitates the edema formation. Edema results in 'no-reflow' phenomenon.

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