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Table 1 Substances distributed to brain by transport at the blood-CSF gateway

From: Homeostatic capabilities of the choroid plexus epithelium in Alzheimer's disease

Class or group

Examples

Functions

References

Neuropeptides

Arginine vasopressin

Regulation of CSF formation

[8–11]

Growth factors

Basic fibroblast growth factor

Integration of water balance

[55, 104]

Trace elements

Iron

Enzyme function in neurons/glia

[1, 12]

Vitamins

Ascorbate & folate

Antioxidants & co-factors for brain

[13, 14]

Nucleoside bases

Thymidine

Nucleic acids & drug transport

[15, 16]

Protease inhibitors

Cystatin C

Neuroprotection after ischemia

[1, 17]

Hormones

Prolactin & leptin

Modulation of hypothalamus

[18, 19]