FGF receptor expression in human CP: Lateral ventricle plexuses obtained from pathologically-confirmed AD subjects were immersion-fixed in paraformaldehyde, cryoprotected and stored at -70°C. CP segments were free-floated for 72–96 hr in a 1/500 polyclonal antibody against the FGFr, which recognizes all FGF receptor subtypes. Specific staining was established by antibody omission/preabsorption . ABC peroxidase/diaminobenzidine technique was used. Arrowhead points to small punctated dots of immunoreactivity. Localization of FGFr is described in text. Images are typical of those obtained from 8 controls and 8 AD specimens, respectively.