About our Editors
Helga de Vries, Editorial Board Member
MS center Amsterdam, VU medical center, Netherlands
Find publications in PubMed
Dr Helga E de Vries is full professor at the Department of Molecular Cell Biology and Immunology of the VU University Medical Center, Amsterdam, The Netherlands. Her research group is embedded within the Neuroscience Campus Amsterdam, where she is the current program leader of the research line neuro-inflammation.
The research team of Helga de Vries is focussed on the identification of the molecular and cellular pathways that underlie vascular alterations in neuro-inflammatory and neurodegenerative disorders in a translational setting. Key research is dedicated on studying structure and function of the blood-brain barriers and surrounding cell types during neuro-inflammatory and neurodegenerative disorders such as multiple sclerosis and capillary cerebral amyloid angiopathy, as it occurs in Alzheimer’s disease. Importantly, neuropathological alterations that follow BBB damage and inflammation such as oxidative stress and astrocyte activation are under investigation. More fundamental research within her group is on the identification of underlying molecular mechanisms of barrier regulation, in particular microRNAs, and leukocyte trafficking into the central nervous system.
Helga de Vries is member of the steering committee of the International Brain Barrier Society and she is chair of the Dutch society for brain barrier research, BBB Nedwork (www.bbbnedwork.nl).