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  1. In human neonatal high pressure hydrocephalus (HPHC), diffuse white matter injury and gliosis predispose to poor neuro-developmental outcome. The underlying mechanism for diffuse white matter damage in neonata...

    Authors: Deborah A Sival, Ursula Felderhoff-Müser, Thomas Schmitz, Eelco W Hoving, Carlo Schaller and Axel Heep

    Citation: Cerebrospinal Fluid Research 2008 5:21

    Content type: Research

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  2. Although fibroblast growth factor (Fgf) signalling plays crucial roles in several developing and mature tissues, little information is currently available on expression of Fgf2 during early choroid plexus deve...

    Authors: Sarah Greenwood, Adam Swetloff, Angela M Wade, Tetsuya Terasaki and Patrizia Ferretti

    Citation: Cerebrospinal Fluid Research 2008 5:20

    Content type: Research

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  3. Eosinophilic meningoencephalitis caused by the helminth Angiostrongylus cantonensis, is an emerging infectious disease in America. The objective of this paper was to determine if the intrathecal synthesis of immu...

    Authors: Barbara Padilla-Docal, Alberto J Dorta-Contreras, Raisa Bu-Coifiu-Fanego, Hermes Fundora Hernández, Jesús Callol Barroso and Consuelo Sanchez-Martinez

    Citation: Cerebrospinal Fluid Research 2008 5:18

    Content type: Research

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  4. Detailed human studies of the mechanisms and development of shunt infection in real time are not possible, and we have developed a canine hydrocephalus model to overcome this. The intention of this pilot study...

    Authors: Roger Bayston, Christine Brant, Stephen M Dombrowski, Geraldine Hall, Marion Tuohy, Gary Procop and Mark G Luciano

    Citation: Cerebrospinal Fluid Research 2008 5:17

    Content type: Research

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  5. There is mounting evidence that spinal fluid absorption takes place not only at the arachnoid villi, but also at several extracranial sites, which might serve as a reserve mechanism for, or be primarily involv...

    Authors: Matthias Rammling, Meenu Madan, Leena Paul, Babak Behnam and Jogi V Pattisapu

    Citation: Cerebrospinal Fluid Research 2008 5:15

    Content type: Research

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  6. The objective was to assess the utility of total tau protein (tTau), the ratio of (tTau)/181 phosphorylated tau protein (P-Tau) and 14-3-3 protein, as diagnostic markers in cerebrospinal fluid (CSF) for Creutz...

    Authors: Anders Skinningsrud, Vidar Stenset, Astrid S Gundersen and Tormod Fladby

    Citation: Cerebrospinal Fluid Research 2008 5:14

    Content type: Research

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  7. The cerebral cortex may be compressed in hydrocephalus and some experiments suggest that movement of extracellular substances through the cortex is impaired. We hypothesized that the extracellular compartment ...

    Authors: Marc R Del Bigio and Terry L Enno

    Citation: Cerebrospinal Fluid Research 2008 5:12

    Content type: Research

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  8. We compared cerebrospinal fluid (CSF) opening pressure measurements in the lumbar subarachnoid space between the flexed position (F-OP) and relaxed position (R-OP) in recumbent patients. We devised an equation...

    Authors: Pasiri Sithinamsuwan, Nakorn Sithinamsuwan, Sirakarn Tejavanija, Chesda Udommongkol and Samart Nidhinandana

    Citation: Cerebrospinal Fluid Research 2008 5:11

    Content type: Short paper

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  9. This review integrates eight aspects of cerebrospinal fluid (CSF) circulatory dynamics: formation rate, pressure, flow, volume, turnover rate, composition, recycling and reabsorption. Novel ways to modulate CS...

    Authors: Conrad E Johanson, John A Duncan III, Petra M Klinge, Thomas Brinker, Edward G Stopa and Gerald D Silverberg

    Citation: Cerebrospinal Fluid Research 2008 5:10

    Content type: Review

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  10. The aim of this study was to explore biochemical changes in the cerebrospinal fluid (CSF) induced by shunt surgery and the relationship between these changes and clinical improvement.

    Authors: Mats Tullberg, Kaj Blennow, Jan-Eric Månsson, Pam Fredman, Magnus Tisell and Carsten Wikkelsö

    Citation: Cerebrospinal Fluid Research 2008 5:9

    Content type: Research

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  11. The Polaris valve is a newly released hydrocephalus shunt that is designed to drain cerebrospinal fluid (CSF) from the brain ventricles or lumbar CSF space. The aim of this study was to bench test the properti...

    Authors: David M Allin, Marek Czosnyka, Hugh K Richards, John D Pickard and Zofia H Czosnyka

    Citation: Cerebrospinal Fluid Research 2008 5:8

    Content type: Research

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  12. Prostaglandin E2 (PGE2) is involved in the regulation of synaptic activity and plasticity, and in brain maturation. It is also an important mediator of the central response to inflammatory challenges. The aim of ...

    Authors: Eudeline Alix, Charlotte Schmitt, Nathalie Strazielle and Jean-François Ghersi-Egea

    Citation: Cerebrospinal Fluid Research 2008 5:5

    Content type: Research

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  13. Fetal spina bifida aperta (SBA) is characterized by a spinal meningomyelocele (MMC) and associated with cerebral pathology, such as hydrocephalus and Chiari II malformation. In various animal models, it has be...

    Authors: Olga A de Wit, Wilfred FA den Dunnen, Krystyne M Sollie, Rosa Iris Muñoz, Linda C Meiners, Oebele F Brouwer, Esteban M Rodríguez and Deborah A Sival

    Citation: Cerebrospinal Fluid Research 2008 5:4

    Content type: Research

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  14. The subcommissural organ (SCO) is a highly conserved brain gland present throughout the vertebrate phylum; it secretes glycoproteins into the cerebrospinal fluid (CSF), where they aggregate to form Reissner's ...

    Authors: Karin Vio, Sara Rodríguez, Carlos R Yulis, Cristian Oliver and Esteban M Rodríguez

    Citation: Cerebrospinal Fluid Research 2008 5:3

    Content type: Research

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  15. Matrix metalloproteinases (MMPs) are enzymes that promote tumor invasion and angiogenesis by enzymatically remodeling the extracellular matrix. MMP-2 and MMP-9 are the most abundant forms of MMPs in malignant ...

    Authors: Eric T Wong, David Alsop, Diana Lee, Angela Tam, Loretta Barron, Julianne Bloom, Shiva Gautam and Julian K Wu

    Citation: Cerebrospinal Fluid Research 2008 5:1

    Content type: Research

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  16. There is an increasing interest in using choroid plexus (CP) epithelial cell lines to study the properties of the blood-cerebrospinal fluid barrier (BCSFB). Currently, there are three major CP-derived cell lin...

    Authors: Joanna Szmydynger-Chodobska, Crissey L Pascale, Andrew N Pfeffer, Cassaundra Coulter and Adam Chodobski

    Citation: Cerebrospinal Fluid Research 2007 4:11

    Content type: Research

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