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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Mouse embryonic stem cell-derived blood–brain barrier model: applicability to studying antibody triggered receptor mediated transcytosis

Fig. 1

Schematic detailing mESC-D3 differentiation strategy to generate brain-endothelial-like cells and transwell BBB model in vitro. Schematic diagram of mESC-D3 directed monolayer differentiation protocol via initial mesodermal induction and subsequent endothelial cell differentiation and maturation. Representative phase contrast images illustrating morphological changes accompanying the various stages (Days) of differentiation

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