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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Inhibition of lysophosphatidic acid receptor 1 relieves PMN recruitment in CNS via LPA1/TSP1/CXCR2 pathway and alleviates disruption on blood-brain barrier following intracerebral haemorrhage in mice

Fig. 3

AM966 reduced the recruitment of PMN perihematomal region at 24 h post-ICH. (A) Representative images of immunofluorescence staining of Ly6G (red) and CD11b (green) in the perihematomal region at 24 h post-ICH (Scale bar = 50 μm). (B) Brain sample with identification of the areas (marked with box) used for Ly6G/ CD11b positive cell counting in the perihematomal region. C, Quantitative analyses of Ly6G/ CD11b -positive cells in the perihematomal region at 24 h post- ICH D. One-way ANOVA, Tukey’s test, mean ± SD (error bars). n = 6 per group *P < 0.05 vs. sham group; #P < 0.05 vs. ICH + Vehicle group

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Fluids and Barriers of the CNS

ISSN: 2045-8118