Skip to main content

Table 2 125I-insulin blood-to-brain pharmacokinetics following ICV insulin

From: Central nervous system insulin signaling can influence the rate of insulin influx into brain

Brain

Group

Ki (µl/g-min)

p

r

Vi (µl/g)

Whole

Brain

Vehicle

0.71 ± 0.14

0.037

0.72

5.9 ± 1.5

Insulin

0.30 ± 0.11

0.50

7.9 ± 1.5

Olfactory

Bulb

Vehicle

1.93 ± 0.25

< 0.0001

0.86

5.5 ± 2.5

Insulin

0.35 ± 0.16

0.45

14.6 ± 2.2

  1. Data in this table are generated from the analysis of the graphs in Fig. 5
Back to article page

Fluids and Barriers of the CNS

ISSN: 2045-8118