Fig. 6
From: Central nervous system insulin signaling can influence the rate of insulin influx into brain
125I-insulin blood-to-brain transport following ICV S961. 125I-insulin BBB pharmacokinetics were assessed 10 min after 1 µl ICV injection of vehicle (PB) or S961 (1 µg) in the A/B) whole brain, C/D) olfactory bulb, and E/F) hypothalamus in males (A, C, E) and females (B, D, F). See Table 3 for pharmacokinetic calculations. Each data point represents a single mouse. Ki *p < 0.05 as marked