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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Movement of cerebrospinal fluid tracer into brain parenchyma and outflow to nasal mucosa is reduced at 24 h but not 2 weeks post-stroke in mice

Fig. 4

CSF tracer efflux into the nasal mucosa via the cribriform plate. (A) Schematic indicating the four levels of sections taken from the mouse nose. (B) Representative images of fluorescent CSF tracer distribution and load in the nasal mucosa 24 h after photothrombotic stroke. (C) Fluorescent tracer load as a percent of total tissue area at each of the four levels 24 h after stroke. (D) Representative images of fluorescent CSF tracer distribution and load in the nasal mucosa two weeks after photothrombotic stroke. (E) Fluorescent tracer load as a percent of total tissue area at each of the four levels 2 weeks after photothrombotic stroke (E). **** p < 0.001, ** p < 0.01, *p < 0.05. Schematic created with BioRender.com

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