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Table 4 CSF production rates calculated by the 3D and 1D models with the parameter values given in Table 3

From: Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis

Case

3D model (µL/min)

1D model (µL/min)

1D/3D ratio (–)

Active surface ratio (–)

Mean − SD

0.0013

0.0025

1.886

0.502

Mean

0.0053

0.0067

1.273

0.781

Mean + SD

0.0073

0.0109

1.494

0.651

  1. A larger 1D/3D ratio indicates a stronger overestimation of CSF production by the 1D model. The active surface ratio is defined as the surface area through which solutes enter the FU divided by the overall FU surface area
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Fluids and Barriers of the CNS

ISSN: 2045-8118