Table 3 3D model parameters, obtained from the 1D model with zero protected length
Parameters | Symbol | Value | ||
|---|---|---|---|---|
Mean − SD | Mean | Mean + SD | ||
Microvillus length (µm) | \({l}_{\text{mv}}\) | 2.329 | 1.875 | 1.959 |
Microvillus radius (µm) | \({r}_{\text{mv}}\) | 0.087 | 0.104 | 0.098 |
Microvilli surface density (1/µm2) | \(\sigma\) | 10.0 | 15.3 | 12.6 |
ChP apparent area (cm2) | \({A}_{\text{app}}\) | 3.54 | 3.85 | 3.87 |
Protected length (µm) | \({l}_{\text{prot}}\) | 0 | 0 | 0 |
Diffusion coefficient (cm2/s) | \(D\) | 1.12 · 10–5 | 1.06 · 10–5 | 1.08 · 10–6 |
Bulk solute concentration (Osm) | \({C}_{0}\) | 0.2967 | 0.3129 | 0.3041 |
Luminal membrane permeability (cm/s · Osm) | \({L}_{\text{p}}\) | 5.03 ·  10–6 | 9.82 · 10–6 | 2.17 · 10–5 |
CSF density (g/mL) | \(\rho\) | 1.0002 | 1.0001 | 1.0002 |
Measured CSF production rate (µL/min) | \({Q}_{\text{meas}}\) | 7.071 | 7.346 | 7.072 |
CSF viscosity (Pa · s) | \(\mu\) | 8.9 · 10–4 | 8.9 · 10–4 | 8.9 · 10–4 |