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Table 1 Parameter values used for comparing results of the current 1D SG model to the original standing gradient one

From: Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis

Parameters

Symbol

Value

Microvillus length (µm)

\({l}_{\text{mv}}\)

100

Hydraulic diameter (µm)

\(d\)

0.1

Protected length (µm)

\({l}_{\text{prot}}\)

0

Diffusion coefficient (cm2/s)

\(D\)

10–5

Luminal membrane permeability (cm/s Osm)

\({L}_{\text{p}}\)

2 · 10–4

Bulk solute concentration (Osm)

\({C}_{0}\)

0.3

CSF density (g/mL)

\(\rho\)

1.00

Solute flux (mmol/s · cm2)

\(\phi\)

10–5 for \(z\le 0.1 {l}_{\text{mv}}\)

0 for \(z>0.1 {l}_{\text{mv}}\)

  1. The solute flux depends on the location in the FU. These values correspond to those originally used by Diamond and Bossert and are not representative of the ChP