Skip to main content
Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Role of interleukin-6 and interleukin-10 in morphological and functional changes of the blood–brain barrier in hypertriglyceridemia

Fig. 2

Effects of cytokine treatments on the function of brain microvascular endothelial cells. a TEER values in wild type (WT) and apolipoprotein B-100 (APOB-100) endothelial cell cultures treated with Il-6, IL-10, and their combination. b Permeability for sodium fluorescein (SF) in WT and APOB-100 endothelial cell cultures under control conditions and following cytokine treatments. c Activity of the efflux pump P-glycoprotein in WT and APOB-100 endothelial cell cultures. R123: rhodamine 123; CYA: cyclosporin A. #: significant change between WT and APOB-100 cells (p < 0.05); *: significant change due to cytokine treatment compared to the control group with the same genotype (p < 0.05); xxxx: significant change due to cyclosporin A (p < 0.0001)

Back to article page

Fluids and Barriers of the CNS

ISSN: 2045-8118