Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion

Table 1 Clinical characteristics of the study population

	Healthy volunteer			iNPH patient	P-value^a	P-value^b
	< 40 years	40–59 years	≥ 60 years	iNPH patient	P-value^a	P-value^b
Total number	47	49	36	36
Sex (male: female)	16:31	15:34	15:21	25:11	0.032	0.577
Mean age (years)	29.3 ± 5.5	49.1 ± 5.9	69.3 ± 6.8	76.8 ± 7.5	< 0.001	< 0.001
Total subarachnoid space (mL)	213.7 ± 44.3	244.1 ± 52.4	305.6 ± 58.0	291.2 ± 61.4	0.336	< 0.001
Total ventricle (mL)	21.3 ± 7.1	23.7 ± 8.3	37.7 ± 14.2	130.1 ± 38.8	< 0.001	< 0.001
Evans index	0.25 ± 0.02	0.25 ± 0.02	0.26 ± 0.02	0.37 ± 0.20	< 0.001	0.034
Z-Evans index	0.24 ± 0.03	0.24 ± 0.03	0.27 ± 0.04	0.41 ± 0.04	< 0.001	< 0.001
BVR at AC	2.1 ± 0.3	2.1 ± 0.3	1.8 ± 0.4	0.8 ± 0.1	< 0.001	< 0.001
BVR at PC	4.8 ± 1.4	4.3 ± 1.1	3.0 ± 1.0	1.0 ± 0.2	< 0.001	< 0.001
Callosal angle (degree)	119.9 ± 9.2	118.6 ± 11.3	117.1 ± 11.5	68.1 ± 17.3	< 0.001	0.594

Gender differences were compared by Fisher's exact test
AC anterior commissure, PC posterior commissure
^aP-value: probability value for the Mann–Whitney-Wilcoxon test between iNPH patients and healthy volunteer aged ≥ 60 years
^bP-value: probability value for the Kruskal–Wallis test among 3 age groups of healthy volunteer

ISSN: 2045-8118