Fig. 4
Aging impacts number and activation state of cells of the innate and adaptive immune system. A Based on Ingenuity “disease and function” analysis, functions related to cells of the immune system were selected and their activation z-score as well as the number of genes for each affected function were plotted. B Using GO term analysis, a list of genes related to cytokines and chemokines was assembled and functionally annotated. Shown are genes differentially expressed between young and aged meninges