Fig. 6

Partial hepatectomy influences NVC. A Colormap corresponds to the activation map related ∆CBF changes during whisker stimulations in tPA^Null mice and their littermate in sham and ligatured conditions 24 h after partial hepatectomy. Warm colours indicate an elevation of CBF during whisker stimulations. B, C Time course of % CBF increase (mean ± SEM) during whisker stimulations () in tPA^Null mice (C) and their littermate (B), in sham (/) or ligatured (/) conditions. D Box plots show the variation of % CBF increase from baseline during whisker stimulations in tPA^Null mice and their littermate in sham and ligatured conditions. Box plots with medians, 1st and 3rd quartiles, min and max with values for each mouse. E Mean ± SEM representing ELISA analyses of total tPA in tPA^Null mice and their littermate in sham and ligatured conditions (n = 4 for each group). 24 h after partial hepatectomy, plasma samples were collected and subjected to ELISA analysis. *p < 0.05 from sham tPA^WT, Kruskal–Wallis and Uncorrected Dunn’s tests, n = 4 sham tPA^WT, n = 9 ligatured tPA^WT, n = 5 sham tPA^Null, n = 10 ligatured tPA^Null