Fig. 4From: Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood–brain barrierLPS and ssRNA increase BCRP protein levels in human primary fetal brain endothelial cells (hfBECs), in a gestational-age dependent manner. A Representative Western blot images and B–G densitometric analysis of BCRP total protein levels, normalized to ERK2 (loading control for total protein), in early and mid-gestation hfBECs following treatment with LPS (0.01 µg/mL), Poly I:C (1 µg/mL), ssRNA (0.001 µg/mL) or vehicle for 24 h. Data are expressed as means ± SD. N = 6/group. Statistical differences were tested using a paired t-test. *p < 0.05Back to article page