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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Elevated neurofilament light chain CSF/serum ratio indicates impaired CSF outflow in idiopathic intracranial hypertension

Fig. 2

QNfL levels are elevated in IIH patients only. S-NfL levels were increased in MS patients and PNP patients (A), whereas CSF-NfL levels were increased in all patient groups, compared to the non-neurological controls (HC) (B). The CSF/serum ratio of NfL (QNfL) was only increased in IIH patients (C). Horizontal lines of the boxplots denote the median; boxes extend from the 25th to 75th percentile, whiskers from 10 to 90th percentile; individual data points are below the 10th or above the 90th percentile; **p < 0.01, ****p < 0.0001. CSF-NfL cerebrospinal fluid neurofilament light chain, HC healthy controls, IIH idiopathic intracranial hypertension, PNP polyneuropathy, MS multiple sclerosis, QNfL CSF/serum ratio of neurofilament light chain, S-NfL serum neurofilament light chain

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Fluids and Barriers of the CNS

ISSN: 2045-8118