Fig. 6

hpBMEC and hiBMEC had similar glycolytic responses to ACM and high glucose, but not fluvastatin. Glucose uptake and lactate production of hpBMEC compared to hiBMEC following a 24-h treatment with A 0 or 20% ACM, D 5.5 mM or 25 mM glucose, or G 0 nM or 500 nM fluvastatin, measured by YSI. n = 6 biological replicates. Seahorse Glycolytic Rate Assay and Mito Stress Test, with analysis of basal GlycoPER and OCR, of hpBMEC compared to hiBMEC following a 24-h treatment with B, C 0 or 20% ACM, E, F 5.5 mM or 25 mM glucose, or (H-I) 0 nM or 500 nM fluvastatin. n = 15 biological replicates. *p < 0.05 using a Mann–Whitney test