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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Modulation of striatal glutamatergic, dopaminergic and cholinergic neurotransmission pathways concomitant with motor disturbance in rats with kaolin-induced hydrocephalus

Fig. 5

Intracellular dye-injection and substance P immunolabeling of MSNs. A A representative LY-filled MSN in a 60-μm-thick section of the injected brain slice from an age-matched control rat of the acute hydrocephalus. The section was also reacted immunohistochemically for substance P. This intracellular dye-filled neuron had a typical MSN morphology. Arrowheads show examples of the substance P-labeled MSN cell bodies without intracellular dye injection in the same section. Substance P-immunoreaction product is in the perinuclear cytoplasm. Insets (a) and (b) show representative magnified views of a proximal and distal dendritic segment of the LY-filled MSN in (A). B High-power view of the cell body of the LY-filled MSN in A shows the absence of perinuclear substance-P immunoreaction product. C A LY-filled MSN concurrently immunolabeled with substance P. Notice the dark perinuclear immunoreaction product. Scale bar = 20 μm in (A) and 10 μm for (B, C) and insets (a) and (b)

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Fluids and Barriers of the CNS

ISSN: 2045-8118