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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40?

Fig. 3

Correlations between Aβ measurements with two different detection antibodies. A The CSF Aβ1–40 concentrations are plotted against the CSF AβX–40 concentrations. B The CSF Aβ1–42 concentrations are plotted against CSF AβX–42 concentrations. C The Aβ1–42/1–40 ratios in CSF are plotted against the AβX–42/X–40 ratios. D The Aβ1–40 concentrations in IP-eluates from plasma are plotted against the corresponding AβX–40 concentrations. E The Aβ1–42 concentrations in IP-eluates from plasma are plotted against the corresponding AβX–42 concentrations. F The Aβ1–42/1–40 ratios are plotted against the corresponding AβX–42/X–40 ratios. The indicated Pearson correlation coefficients (r) and p-values were calculated on log2-transformed data. X- and Y-axes are shown on a logarithmic scale. Solid lines indicate the diagonals (lines of identity) and dashed lines show Deming regressions. Amyloid-positive case are colored in red and amyloid-negative cases in green. amyloid-β, CSF cerebrospinal fluid, IP immunoprecipitation

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