Fig. 4
From: Transcriptomic analysis of a 3D blood–brain barrier model exposed to disturbed fluid flow
A Validation of lumican knockdown efficiency. B-C Immunofluorescence indicating the effect of lumican knockdown (B) on localization of ZO-1 to cell–cell junctions in both fully developed (i) and disturbed (ii) regions, with scrambled siRNA, labeled as "KD" serving as control (C). D Permeability quantification of vessels after 24 h perfusion. Scale bar = 50 μm, * p < 0.05. n = 3 per condition