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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markers

Fig. 3

Comparison between cortex & CSF/plasma concentration ratios of the two markers. Cortex/plasma (filled●) and CSF/plasma (open○) concentration ratios (%) of sucrose (A) and dextran (B) in E16, E19, P4 and adult rats. Samples collected 5 min following i.v. injection of 3H-dextran or 14C-sucrose. Note sucrose CSF ratios were higher than brain ratios in younger animals but dextran ratios were similar at all ages. Mean ± SD, some error bars are too small to be visible; n = 3–6

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Fluids and Barriers of the CNS

ISSN: 2045-8118