Fig. 2From: Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markersSucrose brain and CSF concentration ratios. A Cortex/plasma, B Brainstem/plasma and C CSF/plasma concentration ratios (%) in E16, E19, P4 and adult rats. Samples collected 5 min following i.v. injection of 14C-sucrose. Each point represents result from a single animal. Mean ± SD; n = 3–6. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001Back to article page