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Fig. 8 | Fluids and Barriers of the CNS

Fig. 8

From: Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies

Fig. 8

Modified from Liu et al. [66]

Direct CSF Production Measurement in rodent. A lateral ventricle is cannulated with a glass capillary tube, while a needle is connected to tube inserted into the fourth ventricle and used to infuse 1 μL mineral oil to block the aqueduct of Sylvius. The volume of CSF production is measured from the tube in the lateral ventricle, using the measured volume-time relationship.

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Fluids and Barriers of the CNS

ISSN: 2045-8118