Human intracranial pulsatility during the cardiac cycle: a computational modelling framework

Table 1 Comparison of the generated computational head model and experimentally determined values in healthy subjects with respect to the dimensions of the brain’s substructures; C3 is the third cervical vetrebra level of the spine

Substructure dimension	This study	Literature value	References
Lateral ventricles volume	\(24.01\,\)ml	\(9.82\,\)ml (normal) 250.2 ml (hydrocephalic)	Linninger et al [36]
Third ventricle volume	\(3.60\,\)ml	\(2.48\,\)ml	Linninger et al [36]
Fourth ventricle volume	\(2.69\,\)ml	\(3.31\,\)ml	Linninger et al [36]
Subarachnoid space volume	\(292.08\,\)ml	\(179\,\)ml (only cranial)	Chazen et al [15]
Aqueduct diameter	2.88 mm	1.5 to 3.0 mm	Haines and Mihailoff [28]
Spinal canal (C3) diameter	12 mm	9.4 to 17.2 mm	Ulbrich et al [57]
Spinal coord (C3) diameter	7 mm	6.0 to 9.6 mm	Ulbrich et al [57]
Brain parenchyma total volume	\(1369.54\,\)ml	1130 ml (women) 1260 ml (men)	Cosgrove et al [17]

ISSN: 2045-8118