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Table 4 Sensitivity analysis for \({R}_{LC}\)

From: Mathematical modelling of the CSF system: effects of microstructures and posture on optic nerve subarachnoid space dynamics

Baseline porosity (%)

\({Q}_{LC}/{Q}_{for{m}_{Aqueous Humor}}\)(%) in supine

\({Q}_{LC}/{Q}_{for{m}_{Aqueous Humor}}\)(%) in upright posture

\({p}_{ONSAS}\) in the upright posture (mmHg)

Poiseuille

0.24 (Default)

0.43

− 5.3

5

9

− 5.2

15

27

− 5.1

24

42

− 5.0

0.95

0.24

0.42

− 4.6

5

9

− 4.5

15

26

− 4.4

24

41

− 4.3

0.9

0.24

0.40

− 3.9

5

8

− 3.7

15

25

− 3.5

24

39

− 3.4

0.85

0.24

0.39

− 3.3

5

8

− 3.0

15

24

− 2.8

24

37

− 2.7

0.75

0.24

0.36

− 2.0

5

7

− 1.7

15

22

− 1.4

24

34

− 1.3

  1. The \({R}_{LC}\) was adjusted to allow for specific supine flow rates \({Q}_{LC}\). Resulting upright flow rates are also presented