Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters

Table 1 Transport proteins implicated in CSF secretion. Choroidal RNAseq data are given in transcript per million (TPM) for control rats and PHH rats (n = 4 of each)

Gene	Alias	Description	Control (TPM)	PHH (TPM)	Log₂FC	Upregulated (%)
ATP1A1	NKAα1	Na⁺/K⁺-ATPase α1	392	534	0.44	36
ATP1B3	NKAβ3	Na⁺/K⁺-ATPase β3	196	283	0.53	44
SLC12A2	NKCC1	Na⁺/K⁺/2Cl⁻ cotransporter	200	257	0.36	29
SLC4A10	NCBE	Na⁺/HCO₃⁻ cotransporter	245	306	0.32	25
AQP1	AQP1	Aquaporin 1	482	969	1.01	101

Changes at the transcriptional level are indicated by the log₂ fold-change (Log₂FC) and the upregulation in percent

ISSN: 2045-8118