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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Selective sphingosine-1-phosphate receptor 1 modulator attenuates blood–brain barrier disruption following traumatic brain injury by inhibiting vesicular transcytosis

Fig. 4

Treatment with CYM-5442 improved cerebral blood flow after TBI. A Laser speckle images of TBI mice treated with 3 mg/kg CYM-5442. B Blood flow of the contusional and pericontusional cortices in the regions of interest (ROIs) in TBI mice receiving 3 mg/kg CYM-5442 or Vehicle or Sham treatment. All data was analysed by repeated-measures ANOVA, followed by Tukey’s multiple comparisons test, *P < 0.05, n = 8. Those experimental groups in receipt of the vehicle/CYM-5442 also were subjected to TBI. All values are presented as the mean ± SD

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Fluids and Barriers of the CNS

ISSN: 2045-8118