Fig. 7

Associations between demographic and pharmacokinetic variables in the reference cohort. Associations between time to maximum concentration (T_max), lag-time of absorption (T_lag), half-life of absorption (T_{1/2, abs}), dose-normalized maximum concentration (C_max), dose-normalized area under the curve (AUC _0-Inf) and age, height, and weight in the reference cohort. Associations are presented as Pearson’s rho (r) [95% confidence interval]. * P < 0.05, ** P < 0.01. To aid the reader, values in bold are statistically significant to P < 0.05