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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders

Fig. 5

Inter-individual variation in CSF to blood clearance within each diagnosis category. Individual posterior dose-normalized predicted concentrations of gadobutrol over time for the A reference (REF), B pineal cyst (PC), C arachnoid cyst (AC), D spontaneous intracranial hypotension (SIH), E idiopathic intracranial hypertension (IIH), F idiopathic normal pressure hydrocephalus (iNPH), G communicating hydrocephalus (Comm HC) and H non-communicating hydrocephalus (Non-comm HC) groups. Black lines represent the mean concentration for each group, averaged at each time-point

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