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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders

Fig. 2

Population pharmacokinetic model diagnostic plots. A Observed gadobutrol concentrations against posterior individual predicted concentrations. Dashed and solid lines represent the unity and linear regression line, respectively. B Residual error against time, solid line represents the l. C Residual error against individual observed gadobutrol concentrations, dotted lines represent the treshold for 15% relative error. D Randomly selected patient profiles, with observations (dot) and individual predictions (solid line), demonstrating goodness of fit

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