Fluids and Barriers of the CNS

Table 3 Models for predicting each feature postVPS (after 6 months), given their value at preTT (baseline), or both their value at preTT and their change after the TT (postTT)

From: Gait apraxia evaluation in normal pressure hydrocephalus using inertial sensors. Clinical correlates, ventriculoperitoneal shunt outcomes, and tap-test predictive capacity

	postVPS ~ preTT	postVPS ~ preTT + Δ_postTT-preTT	Likelihood ratio test
	R²_adj	R²_adj	χ²	p-value
Clinical
nSteps2turn	0.13	0.14	1.409	0.235
Tinetti Balance	0.27	0.30	2.661	0.103
Tinetti Gait	0.18	0.17	0.529	0.467
Tinetti Total	0.33	0.41	6.213	0.013
GSS	0.23	0.23	0.637	0.425
iNPH-GS	0.16	0.14	0.083	0.773
TUG
TestDuration	0.11	0.38	16.437	0.0001
TotalSteps	0.29	0.29	0.914	0.339
WalkTime	0.13	0.42	18.151	0.00002
StandTime	-0.02	0.18	10.333	0.001
SitTime	0.00	0.20	10.392	0.001
TurnSteps	0.44	0.43	0.50	0.480
Cadence	0.26	0.39	8.714	0.003
StrideLength	0.48	0.53	5.715	0.017
DoubleSupport	0.35	0.35	1.386	0.239
GaitSpeed	0.28	0.39	8.163	0.004
TrunkInclination	0.30	0.49	14.693	0.0001
maxTC1	0.25	0.23	0.150	0.699
maxTC2	0.18	0.32	8.996	0.003
minTC	0.17	0.32	9.815	0.002
PitchAtTC2	-0.02	0.08	5.465	0.019
pci	0.05	0.19	7.338	0.007
StrideSD	-0.02	0.00	2.016	0.156
psdF	0.48	0.52	3.929	0.047
psdW	0.20	0.28	5.914	0.015
18mW
TestDuration	0.37	0.37	1.214	0.271
TotalSteps	0.52	0.51	0.369	0.544
Cadence	0.38	0.49	8.882	0.003
StrideLength	0.39	0.39	0.792	0.374
DoubleSupport	0.32	0.35	2.761	0.097
GaitSpeed	0.32	0.35	2.761	0.097
TrunkInclination	0.56	0.70	16.055	0.0001
maxTC1	0.27	0.26	0.811	0.368
maxTC2	0.28	0.26	0.016	0.898
minTC	0.31	0.30	0.667	0.414
PitchAtTC2	− 0.03	− 0.05	0.153	0.695
pci	0.05	0.12	4.311	0.038
StrideSD	0.12	0.11	0.281	0.596
psdF	0.27	0.42	10.174	0.001
psdW	0.27	0.43	10.901	0.001

R²_adj indicates the model goodness of fit. Likelihood ratio tests between nested models indicate the added prognostic value of CSF-TT information. Significant p-values (< 0.05) are highlighted in bold

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ISSN: 2045-8118

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