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Table 1 Demographic data, preoperative symptoms, and protein concentrations

From: White matter changes should not exclude patients with idiopathic normal pressure hydrocephalus from shunt surgery

Characteristic Value n
Age, years, mean (range) 75 (50–89) 253
Male, n (%) 141 (56%) 253
Comorbidity, n (%):   
 Diabetes 63 (25%) 253
 Hyperlipidemia 96 (38%) 253
 Hypertension 162 (64%) 253
 Previous AMI 37 (15%) 253
 Previous stroke 32 (13%) 253
Aspirin use, n (%) 102 (40%) 253
Oral anticoagulant drug use*, n (%) 18 (7%) 253
Total iNPH scale score, mean (SD) 49.8 (19.0) 253
Separate domain scores, mean (SD)   
 Balance domain 64.3 (20.9) 244
 Continence domain 59.5 (26.1) 246
 Gait domain 38.9 (24.1) 253
 Cognitive domain 48.9 (21.2) 98
MMSE score, median (IQR) 25.0 (22.0–28.0) 249
Time between preoperative evaluation and surgery, months, median (IQR) 6 (4–8) 253
Protein concentrations, ng/L, median (IQR)   
 T-tau 211 (150–326) 240
 P-tau 30 (23–39) 236
 Aβ1-42 540 (378–708) 237
 NfL 1200 (790–1730) 75
  1. AMI acute myocardial infarction, iNPH idiopathic normal pressure hydrocephalus, SD standard deviation, MMSE mini-mental state examination, IQR interquartile range, ng nanogram, T-tau total tau, P-tau phosphorylated tau, Aβ1-42 amyloid beta1-42, NfL neurofilament light chain protein
  2. *Warfarin or new oral anticoagulants