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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Claudin-5a is essential for the functional formation of both zebrafish blood-brain barrier and blood-cerebrospinal fluid barrier

Fig. 3

Whole-brain oedema, ventricular dilatation, and cerebral hernia in cldn5a-/- with brain edema (BE). Histology of and HE staining on zebrafish brain sections at 22 dpf. In the forebrain and midbrain, cldn5a-/- with BE had a round outline and exhibited serious brain parenchymal edema and exaggerated ventricular dilatation. A yellow dot line labels the brain hernia in cldn5a-/- with BE. Black dot lines describe the brain ventricles. n > 3 brains analyzed per group. Scale bars: 100 μm

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Fluids and Barriers of the CNS

ISSN: 2045-8118