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Table 3 Highly transcribed transporters and pumps in proximal tubule

From: Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus

Gene Alias TPM Description PT Rank CP Rank
SLC7A13 XAT2 7344 Na+-independent aspartate/glutamate transporter 1 N/A
SLC3A1 NBAT 3113 Neutral and basic amino acid transporter 2 98
SLC16A4 MCT5 993 Monocarboxylate transporter 5 3 N/A
SLC13A1 NAS1 384 Na+, SO42− transporter 1 4 N/A
FXYD2 FXYD2 359 Na+/K+ ATPase γ2 5 N/A
PDZD11 PDZD11 279 Plasma membrane Ca2+ ATPase-interacting single-PDZ Protein 6 30
ABCG2 BCRP 164 ATP binding cassette transporter G2 7 209
SLC17A3 NPT4 148 Na+, PO43− transporter 4 8 N/A
SLC5A12 SMCT2 147 Na+-coupled monocarboxylate transporter 2 9 N/A
SLC31A1 CTR1 136 Cu2+ transporter 1 10 8
SLC51B OSTB 131 Organic solute transporter β 11 N/A
ATP1B1 NKA.β1 98 Na+/K+-ATPase β1 12 2
MAGT1 MAGT1 72 Mg2+ transporter protein 1 13 58
SLC34A1 NPT2 67 Na+, PO43− transporter 2 14 N/A
SLC16A12 MCT12 45 Monocarboxylate transporter 12 15 42
SLC22A6 OAT1 29 Organic anion transporter 1 16 N/A
SLC22A2 OCT2 25 Organic cation transporter 2 17 N/A
TMEM30A TMEM30A 24 P4-ATPase flippase β subunit 18 18
SLC15A2 PEPT2 22 Peptide transporter 2 19 87
SLC5A2 SGLT2 22 Na+, glucose cotransporter 2 20 137
  1. RNAseq analysis revealing the 20 highest expressed genes encoding plasma membrane transporters and pumps in proximal tubule. TPM: transcripts per million; PT rank: each gene’s rank in the proximal tubule sample; CP rank: each gene’s rank in the choroid plexus sample; N/A: not applicable if the genes is transcribed below the applied cut-off of 0.5 TPM