Fig. 7

Network analysis of choroidal membrane channels and signaling cascades. Association network between plasma ion and water channels together with receptors (GPCRs and RTKs) and intracellular messengers (kinases, phosphatases, PDEs, and cyclases). The nodes (spheres) are colored based on their protein type. The size of the nodes corresponds to the transcriptional expression level in TPM and illustrates TPM ≤ 10, 10–50, and ≥ 50. The confidence score is indicated by the color of the connecting lines from 0.7 (red) to 1.0 (blue). Only associations from empirical data and curated databases are included