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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers

Fig. 3

Transport of α-syn oligomers through the BBB model. Representative confocal microscopy images of α-syn ONE oligomers uptake in pBEC on filters after 2 h chase. Green color are stains for α-syn oligomers and blue are Hoechst stains. a α-syn oligomer added from luminal side (b) α-syn oligomer added from abluminal side (c). Scale bars show 15 µm. ELISA results for α-syn oligomeric transport across BBB model with 2 h of chase for the indicated directions. Significance was tested using One-way ANOVA with Šidák´s multiple comparisons test

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